Top 25 College Hoops Picks Against the Spread – Wednesday, February 26
Published 2:12 am Wednesday, February 26, 2025
There are nine games featuring a ranked team on Wednesday’s college basketball slate. Below, we provide against-the-spread picks for each contest.
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AP Top 25 Picks ATS Today
No. 16 Maryland Terrapins vs. No. 8 Michigan State Spartans
Spread Prediction
- Computer Prediction: Maryland 76, Michigan State 72
- Projected Favorite: Maryland by 3.7 points
- Pick ATS: Maryland (-3.5)
Bet on the Maryland-Michigan State spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 6:30 p.m. ET
- Location: College Park, Maryland
- Venue: XFINITY Center
- TV Channel: BTN
- Live Stream: (Regional restrictions may apply)
No. 13 Clemson Tigers vs. Notre Dame Fighting Irish
Spread Prediction
- Computer Prediction: Clemson 79, Notre Dame 66
- Projected Favorite: Clemson by 13.4 points
- Pick ATS: Notre Dame (+13.5)
Bet on the Clemson-Notre Dame spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 7 p.m. ET
- Location: Clemson, South Carolina
- Venue: Littlejohn Coliseum
- TV Channel: ACC Network
- Live Stream: (Regional restrictions may apply)
No. 12 Texas A&M Aggies vs. Vanderbilt Commodores
Spread Prediction
- Computer Prediction: Texas A&M 77, Vanderbilt 69
- Projected Favorite: Texas A&M by 7.9 points
- Pick ATS: Texas A&M (-7.5)
Bet on the Texas A&M-Vanderbilt spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 7 p.m. ET
- Location: College Station, Texas
- Venue: Reed Arena
- TV Channel: SEC Network
- Live Stream: (Regional restrictions may apply)
No. 1 Auburn Tigers vs. Ole Miss Rebels
Spread Prediction
- Computer Prediction: Auburn 80, Ole Miss 69
- Projected Favorite: Auburn by 11.1 points
- Pick ATS: Ole Miss (+12.5)
Bet on the Auburn-Ole Miss spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 7 p.m. ET
- Location: Auburn, Alabama
- Venue: Neville Arena
- TV Channel: ESPN2
- Live Stream: (Regional restrictions may apply)
No. 18 Memphis Tigers vs. Rice Owls
Spread Prediction
- Computer Prediction: Memphis 82, Rice 65
- Projected Favorite: Memphis by 16.6 points
- Pick ATS: Memphis (-13.5)
Bet on the Memphis-Rice spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 8 p.m. ET
- Location: Memphis, Tennessee
- Venue: FedExForum
- TV Channel: ESPN+
- Live Stream:
Oklahoma Sooners vs. No. 17 Kentucky Wildcats
Spread Prediction
- Computer Prediction: Kentucky 81, Oklahoma 76
- Projected Favorite: Kentucky by 4.8 points
- Pick ATS: Kentucky (-3.5)
Bet on the Oklahoma-Kentucky spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 9 p.m. ET
- Location: Norman, Oklahoma
- Venue: Lloyd Noble Center
- TV Channel: SEC Network
- Live Stream: (Regional restrictions may apply)
Butler Bulldogs vs. No. 7 St. John’s Red Storm
Spread Prediction
- Computer Prediction: St. John’s 76, Butler 70
- Projected Favorite: St. John’s by 6.5 points
- Pick ATS: Butler (+7.5)
Bet on the Butler-St. John’s spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 9 p.m. ET
- Location: Indianapolis, Indiana
- Venue: Hinkle Fieldhouse
- TV Channel: CBS Sports Network
- Live Stream: (Regional restrictions may apply)
No. 22 Arizona Wildcats vs. Utah Utes
Spread Prediction
- Computer Prediction: Arizona 80, Utah 69
- Projected Favorite: Arizona by 11.9 points
- Pick ATS: Utah (+14.5)
Bet on the Arizona-Utah spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 9 p.m. ET
- Location: Tucson, Arizona
- Venue: McKale Center
- TV Channel: ESPN+
- Live Stream:
Arizona State Sun Devils vs. No. 25 BYU Cougars
Spread Prediction
- Computer Prediction: BYU 75, Arizona State 73
- Projected Favorite: BYU by 2.1 points
- Pick ATS: Arizona State (+4.5)
Bet on the Arizona State-BYU spread—or any other NCAA men’s basketball matchup—with !
Key Facts
- Time: 9:30 p.m. ET
- Location: Tempe, Arizona
- Venue: Desert Financial Arena
- TV Channel: ESPN+
- Live Stream:
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